Coronary Artery Calcium Test (CAC)

What is CAC?

A noninvasive, low-dose, non-contrast CT that measures calcified plaque in the coronary arteries and reports a calcium score.

  • Higher scores = higher future risk of MI and stroke.

  • It doesn’t see soft (non-calcified) plaque, so a low score doesn’t fully exclude CAD—but CAC remains a strong predictor of events.

Why consider it?

  • Helps with ASCVD prevention decisions (e.g., starting a statin or—selectively—low-dose aspirin).

  • Improves risk communication and adherence by showing patients their arterial calcium “number.”


Who Should Get a CAC?

Usually appropriate (shared decision):

  • Age 40–75 with 5–20% 10-year ASCVD risk (borderline to intermediate) when the statin decision is uncertain

  • Patients with multiple risk enhancers (e.g., HTN, smoking, low HDL, CKD, strong FH premature ASCVD), when a result would change management

Generally not appropriate:

  • Known CAD (prior MI, stent, CABG) or active chest pain → use diagnostic pathways, not CAC

  • Very low risk adults

  • <40 years unless compelling history/risk

  • Situations where the result won’t change therapy (e.g., LDL ≥190 or diabetes age 40–75 where statins are indicated regardless)

Cost & radiation: typically $100–$500 (often ~$150); radiation roughly ~1 mSv (low).


How to Interpret the Score

CAC Score Risk Typical Action
0 Very low 10-yr risk Emphasize lifestyle. Defer statin may be reasonable if risk is low/borderline and no high-risk features (e.g., diabetes, smoker, strong FH, persistent LDL ≥160–190). Reassess global risk in a few years.
1–99 Low–mild ↑ risk Consider statin, especially ≥55 y or with risk enhancers. Intensify lifestyle and BP control.
100–399 Moderately–high ↑ risk Start statin (usually moderate–high intensity). Discuss selective low-dose aspirin only if age 40–59 with ≥10% risk and low bleed risk. Optimize BP, weight, and smoking cessation.
≥400 High–severe ↑ risk High-intensity statin, aggressive risk-factor control, consider cardiology referral. Aspirin may be reasonable in carefully selected low-bleed-risk patients.

Aspirin for primary prevention: consider only case-by-case in age 40–59 with ≥10% 10-yr risk and low bleeding risk; generally avoid starting aspirin ≥60 y for primary prevention.


How Often to Repeat?

Only if the result would change management. Typical intervals sometimes used:

  • Low risk (<5%): 5–7 years

  • Borderline/intermediate (5–10%): 3–5 years

  • Diabetes: around 3 years
    (If therapy is already clearly indicated and accepted, no need to repeat.)


What To Do With the Result (Your Game Plan)

All scores:

  • Lifestyle: heart-healthy diet, exercise, smoking cessation, healthy BMI

  • BP optimization and sleep; consider lipoprotein(a) or other risk enhancers if decisions remain uncertain

Medication decisions:

  • Statin: base on score + overall risk (see table).

  • Aspirin: selective primary prevention only (see note above).

  • Consider cardiology referral: CAC ≥400, atypical symptoms, or complex risk.


Patient Counseling Script (copy/paste)

“A CAC scan is a quick, non-contrast CT that shows calcium in the heart arteries. A score of 0 means very low risk in the next 5–10 years; higher scores mean higher risk. We’ll use your number to decide if a statin(and rarely aspirin) will help you avoid a heart attack or stroke. Regardless of the number, lifestyle—food, movement, sleep, and not smoking—remains critical.”


 

 

Education only; use clinical judgment and your local guidelines.

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